The impact of specific and non-specific immunity on the ecology of Streptococcus pneumoniae and the implications for vaccination
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منابع مشابه
The impact of specific and non-specific immunity on the ecology of Streptococcus pneumoniae and the implications for vaccination
More than 90 capsular serotypes of Streptococcus pneumoniae coexist despite competing for nasopharyngeal carriage and a gradient in fitness. The underlying mechanisms for this are poorly understood and make assessment of the likely population impact of vaccination challenging. We use an individual-based simulation model to generalize widely used deterministic models for pneumococcal competition...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society B: Biological Sciences
سال: 2013
ISSN: 0962-8452,1471-2954
DOI: 10.1098/rspb.2013.1939